Clutching at straws i may be, but, as always, I write this in the hope that it may help somebody out there. Please note that I am not promoting the Ardeypharm company in Germany which sell the probiotic containing E. Coli Nissle1917.
A comprehensive stool analysis i did some years ago revealed a deficiency in beneficial e coli bacteria. I found 2 posts on the environmental illness website which discuss beneficial e-coli and they interested me:
quote from an article about e coli:
"A deficiency in this form of probiotic bacteria can result in reduced production of folic acid, the amino acids Tyrosine, Phenylalanine and Tryptophan, SCFAs and also Co-EnzymeQ10"
The administrator of the site posted:
IBS is another common GI condition for which E.coli supplementation (in the form of Mutaflor) has been used successfully in clinical trials. Check out the manufacturer's website for a list of clinical studies on this product -http://www.ardeypharm.de/en/index.php?seite=clinical
The problem is that this product is produced in Germany and is not widely available in many countries. I believe it is not even allowed to be sold in the US at present. To my knowledge it is also the only probiotic supplement containing a beneficial E.coli strain.
The quote you gave on the beneficial effects of E.coli surprised me a bit too. That is some important work it is doing there. Besides impacting methylation and energy metabolism a deficiency would also directly disrupt neurotransmitter metabolism since tyrosine, phenylalanine and serotonin are required to produce noradrenaline, dopamine and serotonin among others!
I am currently trying to obtain this probiotic and used DrMyhill.co.uk to help me order it. I will update on any progress in a few months