Hello Colin
Someone posted this link in another category.
http://www.abcam.com/FMO3-antibody-ab62178.html
Do you think any type of FMO3 on sale to researchers may have some therapautic use now or someday ? (e.g. such as ingesting FMO3 protein)
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Tenacity wrote:Hi,
I replied to the other thread as well. This isn't FM03, it's an antibody that attacks the FM03 protein. It's designed for use in medical experiments on animals.
It would still be interesting to know if Dr Dolphin thinks this kind of animal research (ie the use of animal "models") can tell us anything about treating TMAU, or if he thinks FM03 supplements will ever become available to patients.
Antibodies are produced by our immune system in response to infection by bacteria, viruses, etc and they bind specifically to proteins on those infectious agents to help destroy them. Antibodies can also be produced in the lab to be used as tools. This particular antibody has been made to specifically bind to human FMO3 and has many uses in the lab. To say 'It's designed for use in medical experiments on animals" is not really correct becuase an antibody is used to detect the 'antigen' it binds to - in this case FMO3 - in experiemnts that don't involve animals directly.
As for 'FMO3 supplements' then I'm afraid that's not really viable as FMO3 is a protein which, if ingested, would be digested in the stomach in the same way as any other protein we eat would be digested. I have a freezer full of human FMO3 protein and it can be bought from several companies. However, they're only designed to be used as reagents for lab experiments not, in any way, as a 'supplement' in TMAu.
FADworker wrote:This particular antibody has been made to specifically bind to human FMO3 and has many uses in the lab. To say 'It's designed for use in medical experiments on animals" is not really correct becuase an antibody is used to detect the 'antigen' it binds to - in this case FMO3 - in experiemnts that don't involve animals directly.
Lauren23 wrote:For instance, if one developed TMAU from taking a drug which altered the FMO 3 enzyme, might activating one's telomerase in turn help the enzyme to function properly again?
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